The couple, who have known each other for some 25 years, banned mobile phones at the event. Staff were also sworn to secrecy and 450 police officers were drafted in for the big day.
Antonella looked stunning in a white lace Rosa Clara dress, while Messi was wearing an Armani suit designed by Argentinian designer Claudio Cosano.
Guests chose whether they walked along it to be photographed and interviewed, or went through a discreet side entrance.
Former Barcelona players Xavi Alonso, Cesc Fabregas and Carles Puyol and their wives posed for the world’s press on arrival.
Earlier an aunt of Messi’s was caught out live on TV when an America TV channel called her to interview her about her nephew and she revealed bitterly that she hadn’t been invited to the wedding.
When the woman found out she was live on air she hung up, and when the show called again she answered in tears, blamed Messi’s ‘horrible’ mother Celia for being shafted from the ceremony.